Does OM-3FA supplementation help to prevent cardiovascular diseases?
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Does OM-3FA supplementation help to prevent cardiovascular diseases?
It is a medical review on
Omega-3 fatty acids supplementation:
The purpose of this review :DOES OM-3FA supplementation help to prevent cardiovascular diseases?
1) Introduction (sub-title this section)
a) Find 3 review articles examining fish intake and cardiovascular disease. Briefly summarize the result of these reviews.
B) Briefly describe the different types of OM-3FA.
C) Purpose of this review: does OM-3FA supplementation help to prevent cardiovascular diseases?
2. Effect of OM-3FA on weight gain and obesity (sub- title this section)
a) Use all papers discussed in class. B) add new papers(human and animals studies)
c) put a conclusion at end 1) briefly summarize all findings 2)do the findings agree or disagree?3) what is the ''weight'' of the evidence?
3) Effect of OM-3FA on type 2 diabetes (blood glucose, blood insulin, HOMA index, OGTT, etc.(subtitle this section) A) same instruction as 2 A,B,C123.
4) Effect of OM-3FA on blood pressure and hypertension( subtile this section.
a) Same instruction as 2C a,b,c 123
5. Effect of OM-3FA on blood Lipids (LDL,HDL,Triglycerides, cholesterol.(subtitle this section as in 2 C. a , b, c,123
6. Effect of OM-3FA on inflammation (TNT-alpha, IL-6, other marker of inflammation) (sub title this section)same instructions as 2c a,b,c 123
7. Effect of OM-3FA on atherosclerosis (arteries wall stiffness, wall thickness, calcification, endothelia dysfunction, pulse wave velocity) subtitle this section 2a b, c,
8. Effect of OM-3FA on the metabolic syndrome (Syndrome X) subtitle 2 A,B,C same instruction as 2c
9. Effect of OM-3FA on heart attach , stroke, and mortality ( sub-title this section
2 A,B,C same instruction as 2c
10. CONCLUSION
Briefly summarize the effect of OM-3FA on the cardiovascular system (sub-title this section.
a) List all the main findings from 2-11.
b) What is the'' weight'' of the evidence?
c) Would you recommend or not recommend that people take OM-3FA supplementation.
11.REFERENCE
A) in the reference sections, reference will be listed numerically(eg 1.2.3......) in order of appearance from your paper and in correct format. see attachment.
B) In the body of your paper, reference will be cited, in bracket and in order of appearance (eg [1],[2],[3],...)see attachment.
SPECIAL INSTRUCTIONS
A) use all of the research articles handed out in clss
B) add 12 articles examining the effect of OM-3FA on the cardiovascular system.
1. Scientific research paper
2 can have more than 10 articles (extra credit)
3 NOT WEBSITE ARTICLES
4 NOT REVIE ARTICLES
5 NOT META -ANALYSES
NOTE: HOW TO DISCUSS A RESEARCH PAPER
1) About 3-4 sentences describe the methods.
2)3-4 sentences describe the main finding
3. Do not use quotations; restate in your own words
4 must be cited correctly
I WILL UPLOAD THE 4 ARTICLES HE HANDED OUT IN CLASS .
1) Effects of Prescription Omega-3-Acid Ethyl Esters on Fasting Lipid Profile in
Subjects with Primary Hypercholesterolemia
Maki, Kevin C PhD; Lawless, Andrea L MD; Kelley, Kathleen M MD; Dicklin, Mary R PhD; Kaden, Valerie N; Schild, Arianne L MS; Rains, Tia M PhD; Marshall, John W RN
2)
n–3 Fatty Acids and Cardiovascular Outcomes in Patients with Dysglycemia
The ORIGIN Trial Investigators*
3)
Prognostic Value of Epicardial Coronary Artery Constriction to the Cold Pressor Test in Type 2 Diabetic Patients With Angiographically Normal Coronary Arteries and No
Other Major Coronary Risk Factors
Alain Nitenberg, MD1, Paul Valensi, MD2, Régis Sachs, MD2, Emmanuel Cosson, MD2,
Jean-Raymond Attali, MD2 and Isabelle Antony, MD, PHD3
4) Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis
Author links open overlay
PanelDrMitsuhiroYokoyamaMDaHidekiOrigasaPhDbMasunoriMatsuzakiMDcYujiMatsuzawaMDdYasushiSaitoMDeYuichiIshikawaMDfShinichiOikawaMDgJunSasakiMDhHitoshiHishidaMDiHiroshigeItakuraMDjToruKitaMDkAkiraKitabatakeMDlNoriakiNakayaMDmToshiieSakataMDnKazuyukiShimadaMDoKunioShiratoMDpfor the Japan EPA lipid intervention study (JELIS) Investigators
5)Docosahexaenoic acid supplementation, vascular function and risk factors for cardiovascular disease: a randomized controlled trial in young adults
A Singhal, J Lanigan, C Storry, S Low… - Journal of the …, 2013 - Am Heart Assoc
Background A high consumption of omega-3 long-chain polyunsaturated fatty acids, and particularly docosahexaenoic acid (DHA), has been suggested to reduce the risk of cardiovascular disease (CVD). However, while DHA supplementation may have benefits for secondary prevention, few studies have investigated the role of DHA in the primary prevention of CVD. Here, we tested the hypothesis that DHA supplementation improves endothelial function and risk factors for CVD. THOSE ARE THE ARTICLES HANDED OUT IN CLASS.
PLEASE FEEL FREE TO EMAIL ME FOR ANY INFORMATION.
THANK YOU FOR YOUR HELP.
I WILL NEED TO HAND IN SOON AS POSSIBLE. THX.
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