Trace some of the preliminary steps leading to the discovery of germ theory taken in the 16th to the early 19th centuries

It wasn't until the nineteenth
century that the true cause of disease, the germ theory, was discovered.  Trace some
of the preliminary steps leading to this discovery taken in the 16th to the early
19th centuries.  Be sure to include Pasteur's work. (Hint-though seemingly wedded to
the humoral theory, physicians such as Fracastorius and onward began to guess at the
existence of hidden or invisible "seeds" as the cause of illness while Leuwenhoek's
microscope enabled researchers to actually see germs).
 
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